Tag Archives: clinical

Data from routine clinical care shows people with HIV have an increased risk of dementia and that it’s diagnosed at a younger age

The risk of dementia in older age is increased by 58% for people living with HIV compared to their HIV-negative peers, according to US research published in the online edition of AIDS. The average age at dementia diagnosis was much younger for people with HIV: 67 years compared to 78 years for people without HIV.… Read More »

Coronavirus Antibody: Clinical Trials of Drugs Are Taking Longer Than Expected

As the coronavirus pandemic continues to wreak havoc in the United States and treatments are needed more than ever, clinical trials for some of the most promising experimental drugs are taking longer than expected. Researchers at a dozen clinical trial sites said that testing delays, staffing shortages, space constraints and reluctant patients were complicating their… Read More »

Clinical Update 2020: Antipsychotic Medications and Risk of Gestational Diabetes

Given the number of younger women using atypical antipsychotic medications, there is an urgent need for more accurate data regarding the reproductive safety of these medications. One important question is whether these newer antipsychotic medications, which have been associated with an increased risk of metabolic syndrome and diabetes, may increase the risk of gestational diabetes… Read More »

Promising treatment to slow kidney disease doesn’t prove out in clinical trial

Historically, half or more of people with type 1 diabetes develop kidney disease, which frequently progresses to kidney failure requiring hemodialysis or a kidney transplant for survival. The high rate of this diabetic complication has dropped slightly in recent years, with the advent of better ways to control blood glucose (sugar) levels and improved blood… Read More »

The fight goes on: Clinical trial shows promising new treatment for rare blood cancer

Lymphoma is a type of blood cancer that develops from lymphocytes (a type of white blood cell). It has many subtypes. A rare subtype, called intravascular large B-cell lymphoma (or IVLBCL) is notably hard to diagnose accurately because the cancerous lymphocytes grow inside small blood vessels, instead of at lymph nodes, and there is no… Read More »

Clinical Update 2020: Melatonin and Pregnancy

Many women experience some degree of sleep disturbance during pregnancy. For a significant number of women, the sleep disruption may be so severe as to require some type of intervention.  Sleep disturbance is not only distressing but there is now evidence that sleep disturbance during pregnancy may predispose certain women to perinatal depression or anxiety.… Read More »